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Biofilm-Resistant Medical Devices
1988 - 1994
The period's research pattern fused infection control, safety, and device innovation to push reliable performance in long-term use. Biofilm formation on indwelling surfaces was identified as the central obstacle, guiding work on cleaning, sterilization, anti-biofilm coatings, and outcome monitoring in venous access devices. Safety, risk, and economic considerations shaped device choice and policy, while advances in design diffusion, robotics-enabled interventions, and biocompatibility-focused materials engineering expanded the field.
• Biofilm-centric understanding of device-associated infections: the studies frame biofilm formation on indwelling surfaces as the central obstacle, emphasizing cleaning/sterilization, anti-biofilm coatings, and outcome tracking in prolonged venous access contexts [1] [19] [14] [15] [5].
• Safety, risk, and economic dimensions of medical devices: analysis of needle-stick injuries, cost implications of safer devices, and venous access safety considerations guiding device choice and policy [3] [6] [15] [20].
• Innovation, design, and diffusion in the medical devices industry: historical development of new devices, industry governance, and adoption patterns across implants and robotics [2] [11] [9] [10] [20].
• Robotic and catheter-based interventions and device-enabled surgeries: emergence of robot-assisted prostatic procedures and transcatheter device therapies shaping surgical practice [9] [17].
• Biocompatibility, materials engineering, and energy/functional implants: energy harvesting implants, silicone-based devices, catheter materials, and surface coatings addressing biocompatibility and performance [7] [8] [12] [13] [14].
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